Lichen planus - 扁平苔藓
双胫骨上的广泛病变不典型。在这种情况下，通常更怀疑其他慢性过敏性疾病（lichen simplex chronicus）。
Atrophic lichen planus
relevance score : -100.0%
ReferencesLichen planus (LP) 是一种慢性炎症性疾病，主要影响中年成年人。它可出现在皮肤或黏膜上，如口腔、阴道、食道、喉部和眼睑。根据皮疹的外观和出现部位，LP 有不同的亚型。研究表明，某些类型的 LP——例如累及食道或眼睛的——可能难以被充分诊断。某些形式的 LP，如口腔中的肥厚型和糜烂型，往往负担较重且持续时间较长。药物或接触某些物质等因素也可能诱发类似皮疹。
Lichen planus (LP) is a chronic inflammatory disorder that most often affects middle-aged adults. LP can involve the skin or mucous membranes including the oral, vulvovaginal, esophageal, laryngeal, and conjunctival mucosa. It has different variants based on the morphology of the lesions and the site of involvement. The literature suggests that certain presentations of the disease such as esophageal or ophthalmological involvement are underdiagnosed. The burden of the disease is higher in some variants including hypertrophic LP and erosive oral LP, which may have a more chronic pattern. LP can significantly affect the quality of life of patients as well. Drugs or contact allergens can cause lichenoid reactions as the main differential diagnosis of LP.
Lichen planus (LP) is a chronic inflammatory disorder that most often affects middle-aged adults. LP can involve the skin or mucous membranes including the oral, vulvovaginal, esophageal, laryngeal, and conjunctival mucosa. It has different variants based on the morphology of the lesions and the site of involvement. The literature suggests that certain presentations of the disease such as esophageal or ophthalmological involvement are underdiagnosed. The burden of the disease is higher in some variants including hypertrophic LP and erosive oral LP, which may have a more chronic pattern. LP can significantly affect the quality of life of patients as well. Drugs or contact allergens can cause lichenoid reactions as the main differential diagnosis of LP.
Lichen planus 是一种以紫色、平顶的肿块和斑块为特征的皮肤疾病，可引起剧烈瘙痒。这些皮肤损伤常令人痛苦，尤其是当它们严重累及口腔或生殖器时。在严重情况下， oral lichen planus 甚至可能增加皮肤癌的风险。它还可能影响头皮和指甲。虽然大多数病例的病因尚不明确，但部分病例可能与某些药物或丙型肝炎感染有关。治疗通常对局部病变使用强效药膏，对广泛病变则采用口服类固醇。
Lichen planus is a skin condition marked by purplish, flat-topped bumps and patches that can cause intense itching. These skin lesions can be distressing, especially when they affect the mouth or genitals severely. In severe cases, oral lichen planus may even increase the risk of developing a type of skin cancer. It can also affect the scalp and nails. While the cause of most cases is unknown, some may be triggered by certain medications or hepatitis C infection. Treatment typically involves strong creams for localized cases and oral steroids for more widespread ones.
Lichen planus is a skin condition marked by purplish, flat-topped bumps and patches that can cause intense itching. These skin lesions can be distressing, especially when they affect the mouth or genitals severely. In severe cases, oral lichen planus may even increase the risk of developing a type of skin cancer. It can also affect the scalp and nails. While the cause of most cases is unknown, some may be triggered by certain medications or hepatitis C infection. Treatment typically involves strong creams for localized cases and oral steroids for more widespread ones.
Lichen planus 是一种由免疫系统引起的炎症性疾病，可导致皮肤和黏膜出现明显的损害。约有 5% 的成年人受到影响，女性更常见，通常在中年开始发病。高达 77% 的患者口腔受累，主要表现为内颊黏膜受累。部分患者可能无症状，而另一些患者会感到疼痛，对某些食物（例如酸性、辛辣）或牙膏产生不适。
Lichen planus is an immune-mediated inflammatory condition leading to characteristic lesions on skin and mucous membranes. It presents in up to 5% of the general adult population with a female predilection (2:1); the onset is most commonly in middle age. Up to 77% of patients with lichen planus have oral disease, with buccal mucosa the most common subsite. The oral lesions may be asymptomatic, although a subset of patients have pain and difficulty tolerating certain foods (e.g., acidic, spicy) and toothpaste.
Lichen planus is an immune-mediated inflammatory condition leading to characteristic lesions on skin and mucous membranes. It presents in up to 5% of the general adult population with a female predilection (2:1); the onset is most commonly in middle age. Up to 77% of patients with lichen planus have oral disease, with buccal mucosa the most common subsite. The oral lesions may be asymptomatic, although a subset of patients have pain and difficulty tolerating certain foods (e.g., acidic, spicy) and toothpaste.
确诊皮肤扁平苔藓通常需要进行皮肤活检。对于大疱性病变，可采用直接免疫荧光 (DIF) 来帮助区分本病与其他自身免疫性水疱疾病。